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Hiding in plain sight: an approach to treating patients with severe covid-19 infection

The NQO1-elicited enhancement of whole-body glucose metabolism appears to be mediated, at least in the Keap1 -KO mouse model, by increases in the constitutive NRF2 transcriptional activity, a pleiotropic regulator of the oxidative stress response

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Studies have shown significant changes in the gut microbiota composition of RA patients, which may contribute to their abnormal systemic immune responses